European Markets PCR

The European Markets for PCR Technologies

$ 1,500.00

Since its invention three decades ago, PCR has evolved to become one of the fundamental technology platforms in life sciences sector. The application segments of this platform are still expanding, driven by the expiry of key PCR patents. The demand for fast, accurate, and affordable diagnosis tests in the healthcare segment has been another key driver of the PCR market. The rising investments in the field of companion diagnostics have also been boosting the demand for PCR. Food safety testing is another significant end-use segment of the technology, driven by both consumer demand and regulatory requirements.

In this report “The European Markets for PCR Technologies”, analysts identify the market dynamics in Europe and forecast the potential of the market. The European market, which accounted for approximately 29% of the global demand for PCR technologies, is expected to grow at a CAGR of 7.2% during 2013-2018. The report estimates the market size of the key product and application segments of PCR and forecasts the growth based on market dynamics of these segments, which can impact the demand for PCR. Various technology segments are also analysed in detail.

Product Description

  • Since its invention three decades ago, PCR has evolved to become one of the fundamental technology platforms in life sciences sector. The application segments of this platform are still expanding, driven by the expiry of key PCR patents. The demand for fast, accurate, and affordable diagnosis tests in the healthcare segment has been another key driver of the PCR market. The rising investments in the field of companion diagnostics have also been boosting the demand for PCR. Food safety testing is another significant end-use segment of the technology, driven by both consumer demand and regulatory requirements.

    In this report “The European Markets for PCR Technologies”, analysts identify the market dynamics in Europe and forecast the potential of the market. The European market, which accounted for approximately 29% of the global demand for PCR technologies, is expected to grow at a CAGR of 7.2% during 2013-2018. The report estimates the market size of the key product and application segments of PCR and forecasts the growth based on market dynamics of these segments, which can impact the demand for PCR. Various technology segments are also analysed in detail.

    This study assesses alternate platforms that can potentially impact the demand for PCR. Evolving trends with respect to various aspects of PCR technologies is also analysed in detail. Regulatory landscape of the key regional markets and end-use segments are also included in the report, since regulatory requirements directly impact the demand for PCR based tests.

    Finally, the report analyses the activities of key players in the European markets. Over 60 company profiles are included in the report, which includes leading multinational companies as well as small and medium companies with promising platforms and products.

     

  • INTRODUCTION

    Study Goal and Outline

    Rationale for this Study

    Targeted Audience

    Market Definition and Scope

    Information Sources and Methodologies

    Customization of this study

    Disclaimer

    EXECUTIVE SUMMARY

    CHAPTER 1: OVERVIEW

    Definition Of Polymerase Chain Reaction

    History Of PCR

    Table 1: Timeline Of PCR Technology History (1983 – 2013)

    Table 2: Timeline Of Real-Time PCR History

    Table 3: Timeline Of Digital PCR History

    The Concept

    Important Considerations

    Table 4: Some Important Factors To Be Considered While Planning PCR Experiments

    PCR Platforms – Popular And Emerging

    Allele-Specific PCR (AsPCR)

    Amplified Fragment Length Polymorphisms PCR (Aflp-PCR)

    Assembly PCR

    Asymmetric PCR

    Capillary PCR

    Colony PCR

    Table 5: Key Players And Their Products In The Field Of Colony PCR

    Digital PCR (DPCR)

    Table 6: Key Players And Their Products In The Field Of Digital PCR

    Direct PCR

    Table 7: Key Players And Their Products In The Field Of Direct PCR

    Hot-Start PCR

    Table 8: Key Players And Their Products In The Field Of Hot-Start PCR

    In Situ PCR

    Table 9: Key Players And Their Products In The Field Of In Situ PCR

    Inter-Simple Sequence Repeat PCR (ISSR-PCR)

    Inverse PCR

    Long PCR

    Table 10: Key Players And Their Products In The Field Of Long PCR

    Long Accurate PCR (LAPCR)

    Table 11: Key Players And Their Products In The Field Of Long Accurate PCR

    Methylation-Specific PCR

    Table 12: Key Players And Their Products In The Field Of Methylation-Specific PCR

    Mini Primer PCR

    Multiplex PCR

    Table 13: Key Players And Their Products In The Field Of Multiplex PCR

    Nanoparticle Assisted PCR (Nano PCR)

    Nested PCR

    Table 14: Key Players And Their Products In The Field Of Nested PCR

    Overlap-Extension PCR (OE-PCR)

    Quantitative Fluorescence PCR (QF-PCR)

    Table 15: Key Players And Their Products In The Field Of Quantitative Fluorescence PCR

    Random Amplified Polymorphic Dna (RAPD) PCR

    Table 16: Key Players And Their Products In The Field Of Random Amplified Polymorphic

    DNA PCR

    Real-Time PCR

    Table 17: Commonly Used Detection Chemistries In Real-Time PCR

    Table 18: Key Players And Their Products In The Field Of Real-Time PCR

    Repetitive Sequence-Based PCR (Rep-PCR)

    Reverse Transcription PCR (RT-PCR)

    Table 19: Key Players And Their Products In The Field Of Reverse Transcription PCR

    Single Cell PCR

    Table 20: Key Players And Their Products In The Field Of Single Cell PCR

    Solid Phase PCR

    Thermal Asymmetric Interlaced PCR (TAIL-PCR)

    Touchdown PCR

    Universal Fast Walking PCR (UFW)

    Table 21: Key Players And Their Products In The Field Of Universal Fast Walking PCR

    End-Use Segments Of PCR

    Medical Diagnostics Segments

    Cancer

    Table 22: Key Players Offering PCR-Based Cancer Diagnostics Products In The Market

    Infectious Diseases

    Table 23: Key Players Offering PCR-Based Diagnostics Products Targeting Human Infections

    Prenatal Diagnostics

    Table 24: Key Players Offering PCR-Based Prenatal Diagnostics Products In The Market

    Food Safety Testing, Agricultural, And Environmental Segments

    Food-Borne And Water-Borne Infections

    Table 25: Common Commercial Systems Used For Food Pathogen Detection

    I. Campylobacter And Its Subspecies (Campylobacter Spp.)

    Table 26: International Standards And Guidelines For Campylobacter Spp. Identification

    Table 27: Key Players Offering PCR-Based Kits To Detect Campylobacter And Its Subspecies

    II. Escherichia Coli (E. Coli)

    Table 28: International Standards And Guidelines For Escherichia Coli Detection

    Table 29: Key Players Offering PCR-Based Kits To Detect Pathogenic Escherichia Coli And Its Subspecies

    III. Listeria Monocytogenes And Its Subspecies (Listeria Spp.)

    Table 30: International Standards And Guidelines For Listeria Detection

    Table 31: Key Players Offering PCR-Based Kits To Detect Listeria Monocytogenes And Its Subspecies

    IV. Salmonella And Its Subspecies (Salmonella Spp.)

    Table 32: International Standards And Guidelines For Salmonella Detection

    Table 33:Key Players Offering PCR-Based Kits To Detect Salmonella And Its Subspecies

    V. Other Food-Borne And Water-Borne Pathogens

    Table 34: Key Players Offering PCR-Based Kits To Detect Other Selected Food-Borne And Water-Borne Pathogens

    Veterinary Infection Diagnostics

    Table 35: Key Players Offering PCR-Based Veterinary Diagnostics Products

    Plant Infection Diagnostics

    Table 36: Key Players Offering PCR-Based Diagnostics Products Targeting Plant Infections

    Gmo Foods/Plants Testing

    Table 37: Key Players Offering PCR-Based Kits To Detect GMO Foods/Plants In The Market

    Food Allergens And Animal Species In Food

    Table 38: Key Players Offering PCR-Based Kits To Detect Food Allergens And Animal Species In Food In The Market

    Forensic Sciences

    Table 39: Key Players Offering PCR-Based Human Identity And Forensic Testing Products In The Market

    Life Sciences Research

    miRNA Analysis

    Table 40: Key Players Offering Products For MicroRNA Analysis Involving PCR Technology

    Mutations Detection

    Table 41: Key Players Offering PCR-Based Mutations Detection Products

    SNP Detection And Genotyping

    Table 42: Key Players Offering PCR-Based Products For SNPs Detection And Genotyping

    Sequencing

    Table 43: Key Players Offering PCR-Based Sequencing Products

    Application Of PCR In Ngs Library Quantification

    Table 44: Key Players Offering Ngs Library Quantification Products That Incorporate PCR Technology

    Genetic Fingerprinting

    Table 45: Key Players Offering PCR-Related Products For Genotyping/DNA Fingerprinting

    Site-Directed Mutagenesis (SDM)

    Table 46: Key Players Offering PCR-Based Site-Directed Mutagenesis Products

    Market Trends

    Widening Application Scope

    Patent Expiries During The Forecast Period

    Table 47: Basic PCR Patents Expired In 28 March 2005 In USA

    Table 48: Key Patents In Selected PCR Market Segments And Their Expiry Dates In USA

    Dominance Of PCR Over Alternative Pathogen Diagnostics Options

    Technological Advancements Enabling High Throughput As Well As Point-Of-Care (POC)

    Diagnostics

    Advent Of Digital PCR

    Strong Growth Trends In Single-Cell Analysis (SCA)

    The Rising Demand For Molecular Diagnostics

    The Rising Food Safety Testing Regulations

    Market Drivers

    Table 49: Market Drivers Of The North American PCR Market

    Market Challenges

    Table 50: Market Restraints Of The North American PCR Markets

    The Rising Merger And Acquisition Trends

    Table 51: Key Mergers And Acquisitions During The Past Five Years Relevant In PCR Market (2010-2014)

    CHAPTER 2: INDUSTRY STRUCTURE

    Analysis Of PCR Technology Markets

    Table 52: Global PCR Technology Markets, By Value (USD, Million)

    Figure 1: Market Shares And Forecasts Of Global PCR Technology Market Segments

    The Demand for PCR Technologies in Europe

    Table 53: PCR Market Segments And Their Growth Trends In Europe, By Value (USD, Million)

    Analysis Of Key End-Use Segments

    Table 54: Global PCR Technologies Demand By End-Use Segments, By Value (USD, Million)

    Table 55:PCR Technologies Demand By End-Use Segments In Europe, By Value (USD, Million)

    Medical Diagnostics

    Food, Agriculture, Etc.

    Life Sciences Research

    Figure 2: Market Shares And Forecasts Of PCR Technologies Demand By End-Use Segments

    CHAPTER 3: LEGISLATION AND REGULATION

    MIQE Guidelines And RDML

    Regulatory Landscape Of PCR Technologies In Medical Diagnostics Fields

    Table 56: Regulatory Agencies Responsible For Molecular Diagnostics In Europe

    Table 57: Laws And Regulations Influencing PCR-Based Medical Diagnostics Markets In Europe

    Regulatory Landscape Of PCR Technologies Targeting Food And Agricultural Segments

    Table 58: Main International Agencies Involved In Food Safety Aspects

    Table 59: Selected Regulatory Agencies Responsible For Food Safety and GMO Testing In Europe

    Table 60: Food Safety Laws And Regulations Influencing PCR Technologies Markets In Europe

    CHAPTER 4: TECHNOLOGY TREND ANALYSIS

    Automation Of PCR

    Touch-Screen Options For Ease-Of-Use

    Networking And Remote Controlling Capabilities

    Low Throughput Systems

    Lab-On-A-Chip Formats And Portability

    Application Of Microelectromechanical Systems (Mems) And Convection Principles In PCR

    Automated High Throughput Instruments For Large Scale Applications

    Table 61: Selected Companies Enabling High Throughput In qPCR

    Table 62: Comparison Of The Reaction Formats Of Selected Real-Time PCR Instruments In The Market

    Evolution In Heating Technologies For Efficient Thermal Cycling

    Table 63: Comparison Of The Thermal Modules Of Selected Commercial Real-Time PCR Systems

    Speed

    Detectors

    Light Source

    Table 64: Comparison Of The Optical Modules Of Selected Real-Time PCR Systems In The Market

    Improving Multiplexing Efficiency

    Table 65: Technical Approaches Adopted For Limiting Off-Target Amplification In Multiplex QPCR Assays

    Fluorescence Chemistry

    Taqman Probe

    Molecular Beacons And Scorpions

    Table 66: Fluorescence Chemistry And Multiplex Capability Of Selected QPCR Systems In The Market

    The Early Adopters Of DPCR

    Widening Scope Within Molecular Biology Platforms

    CHAPTER 5: COMPANY PROFILES

    Abacus Diagnostica Oy

    Abbott Laboratories

    Figure 3: Abbott Revenue Shares, by Business Segments, 2013

    ADNucleis

    Affymetrix, Inc.

    Table 67: Affymetrix Revenue Shares, by Business Unit, 2013

    Figure 4: Affymetrix Revenue Shares, by Product Category, 2013

    Agilent Technologies, Inc.

    Figure 5: Agilent Technologies Revenue Shares, by Business Group, 2013

    AlphaHelix Molecular Diagnostics AB

    Altona Diagnostics GmbH

    Ampliqon A/S

    Analytik Jena AG

    AnDiaTec GmbH & Co. KG

    Ares Bioscience GmbH

    Bibby Scientific Limited

    bioMérieux S.A.

    Bio-Rad Laboratories, Inc.

    Figure 6: Bio-Rad Laboratories Revenue Shares, by Region, 2013

    Table 68: Bio-Rad Laboratories Revenue Shares, by Segment, 2013

    BioCat GmbH

    Biogazelle N.V.

    BioGene Ltd.

    Bioline Reagents Limited

    Biolytix AG

    biomers.net GmbH

    BIORON GmbH / BIORON Diagnostics GmbH

    Biotechnological and Medical Laboratories S.A.

    BJS Biotechnologies Ltd.

    Cepheid, Inc.

    Table 69: Clinical and Non-Clinical Revenue Shares, 2013

    Figure 7: Cepheid Revenue Shares, by Region, 2013

    CLONIT srl

    CONGEN Biotechnologie GmbH

    Devyser AB

    Ecoli s.r.o

    ELITech Group

    Enigma Diagnostics Limited

    Eppendorf AG

    Figure 8: Eppendorf Revenue Shares, by Region, 2013

    Eurogentec S.A.

    Exiqon A/S

    F. Hoffmann-La Roche Ltd.

    Table 70: Roche Diagnostics – Main Businesses and their Revenues, 2013

    Figure 9: Roche Diagnostics Revenue Shares, by Region, 2013

    Table 71: Selected PCR-Based Companion Diagnostics under Development by Roche

    Fluorogenics Ltd.

    G-Storm

    GeneON GmbH

    Genekam Biotechnology AG

    GENOMICA S.A.U.

    highQu GmbH

    inno-train Diagnostik GmbH

    Labtech International Ltd.

    LGC Genomics Ltd.

    LIPSDIAG GmbH

    Merck Millipore International

    Figure 10: Merck Millipore Revenue Shares, by Region, 2013

    Table 72: Merck Millipore Revenue Shares, by Business Segments, 2013

    MoBiTec GmbH

    Multiplicom N.V.

    NimaGen B.V.

    PathoFinder B.V.

    PEQLAB Biotechnologie GmbH

    PrimerDesign Ltd.

    Promega Corporation

    QIAGEN N.V.

    Figure 11: Revenue Distribution by Customer Categories, QIAGEN, 2013

    Table 73: Geographic Distribution of QIAGEN Revenues, 2012-2013 (USD, Million)

    Sacace Biotechnologies Srl

    Sigma-Aldrich Corporation

    Table 74: Main Business Units of Sigma-Aldrich and Their Revenue Shares, 2013

    Figure 12: Revenue Shares of Sigma-Aldrich Business Units, by Region, 2013

    Solis BioDyne

    STARLAB Switzerland

    TAG Copenhagen A/S

    Takara Bio, Inc.

    Figure 13: Takara Bio Revenue Shares, by Business Segment, Fiscal Year 2013a

    Table 75: Takara Bio Revenue Shares, by Business Segment, Fiscal Year 2013a

    Thermo Fisher Scientific, Inc.

    Figure 14: Thermo Fisher Scientific Revenue Shares, by Region, 2013

    Figure 15: Life Technologies Revenue Shares, by Region, 2012

    Table 76: Thermo Fisher Scientific Revenue Shares, by Business Segments, 2013a

    Toyobo Co., Ltd

    Table 77: Toyobo Revenue Shares, by Business Segment, Fiscal Year 2013a

  • Abbott Laboratories
    ACTGene, Inc.
    Affymetrix, Inc.
    Agilent Technologies, Inc.
    Ambry Genetics Corporation
    AMRESCO, LLC
    Bio Basic Canada, Inc.
    BioChain Institute, Inc.
    BioControl Systems, Inc.
    bioMérieux S.A.
    Bionexus, Inc.
    Bio-Rad Laboratories, Inc.
    BioServe Biotechnologies Ltd.
    Biotium, Inc.
    Bulldog Bio, Inc.
    Cepheid, Inc.
    E. I. du Pont de Nemours and Company
    Epicentre Biotechnologies (An Illumina Company)
    Epigentek Group, Inc.
    Eppendorf AG
    Eurofins Genomics
    F. Hoffmann-La Roche Ltd.
    Fluidigm Corporation
    Funglyn Biotech, Inc.
    Gene Link, Inc.
    Hercuvan Lab Systems, Inc.
    iCubate, Inc.
    Illumina, Inc.
    Infinigen Biotechnology, Inc.
    InstantLabs
    Integrated DNA Technologies, Inc.
    Invisible Sentinel, Inc.
    Kapa Biosystems, Inc.
    Kestrel BioSciences, LLC
    Lucigen Corporation
    Maxim Biotech, Inc.
    Merck Millipore International
    Molecular Cloning Laboratories (MCLAB)
    New England Biolabs, Inc.
    Norgen Biotek Corporation
    Pall Corporation
    PREMIER Biosoft International
    PrimeraDx, Inc.
    Promega Corporation
    QIAGEN N.V.
    Quanta BioSciences, Inc.
    RainDance Technologies, Inc.
    Scientific Specialties Incorporated
    Sigma-Aldrich Corporation
    Takara Bio, Inc.
    Thermo Fisher Scientific, Inc.
    Toyobo Co., Ltd
    Zoologix, Inc.